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Bacterium magnified 10,000 times.A
microorganism (also spelled as
microrganism) or
microbe is an organism that is
microscopic (too small to be seen by the human eye). The study of microorganisms is called
microbiology. Microorganisms include bacteria, fungi,
archaea or
protists, but not
viruses and prions, which are generally classified as non-living. Most microorganisms are single-
cell (biology)ed, or
unicellular, but some are microscopic, and some unicellular
protists are visible to the average human.
Microorganisms live almost everywhere on Earth where there is liquid water, including hot springs, on the ocean floor, and deep inside rocks within Earth's
crust. Microorganisms are critical to nutrient recycling in
ecosystems as they act as decomposers. As some microorganisms can also
nitrogen fixation, they are an important part of the nitrogen cycle. However,
pathogenic microbes can invade other organisms and cause
diseases that kill millions of people every year. 2002 WHO mortality data Accessed 20 January 2007
History
Evolution
Single-celled microorganisms were the Origin of life to develop on earth, approximately 1 E17 s. Further evolution was slow, and for about 3 billion years in the
Precambrian Eon (geology), all organisms were microscopic. So, for most of the history of life on Earth the only form of life were microorganisms. Bacteria, algae and fungi have been identified in
amber that is 220 million years old, which shows that the morphology of microorganisms have changed little since the
triassic period.
Most microorganisms can reproduce rapidly and microbes such as bacteria can also freely exchange genes by
Bacterial conjugation,
Transformation (genetics) and
Transduction (genetics) between widely-divergent species. This horizontal gene transfer, coupled with a high mutation rate and many other means of
Bacteria#Genetic variation, allows microorganisms to swiftly biological evolution (via natural selection) to survive in new environments and respond to environmental stresses. This rapid evolution has led to the recent development of '
antibiotic resistance' —
pathogenic bacteria that are resistant to modern antibiotics.
Discovery
, the first person to observe microorganisms using a
microscope The existence of microorganisms was hypothesized during the late Middle Ages but they were not observed or proven until the invention of the
microscope in the 17th century. In
The Canon of Medicine (1020),
Abū Alī ibn Sīnā (Avicenna) stated that bodily
secretion is contaminated by foul foreign earthly bodies before being infected, but he did not view them as primary causes of
disease. When the
Black Death bubonic plague reached al-Andalus in the 14th century, Ibn Khatima and Ibn al-Khatib hypothesized that
infectious diseases are caused by microorganisms which enter the human body.Ibrahim B. Syed, Ph.D. (2002). "Islamic Medicine: 1000 years ahead of its times",
The Islamic Medical Association of North America 2, p. 2-9. Such ideas became more popular in Europe during the Renaissance, particularly through the writing of the Italian monk Girolamo Fracastoro.
Prior to
Anton van Leeuwenhoek's discovery of microorganisms in 1675, it had been a mystery as to why
grapes could be turned into wine, milk into
cheese, or why food would spoil. Leeuwenhoek did not make the connection between these processes and microorganisms, but using the microscope, he did establish that there were forms of life that were not visible to the naked eye. Accessed 30 November 2006 Accessed 30 November 2006 Leeuwenhoek's discovery, along with subsequent observations by Lazzaro Spallanzani and Louis Pasteur, ended the long-held belief that life
Abiogenesised from non-living substances during the process of spoilage.
Lazzarro Spallanzani found that microorganisms could only settle in a broth if the broth was exposed to the air. He also found that boiling the broth would
Sterilization (microbiology) it and kill the microorganisms. Louis Pasteur expanded upon Spallanzani's findings by exposing boiled broths to the air, in vessels that contained a filter to prevent all particles from passing through to the growth medium, and also in vessels with no filter at all, with air being admitted via a curved tube that would not allow dust particles to come in contact with the broth. By boiling the broth beforehand, Pasteur ensured that no microorganisms survived within the broths at the beginning of his experiment. Nothing grew in the broths in the course of Pasteur's experiment. This meant that the living organisms that grew in such broths came from outside, as spores on dust, rather than spontaneously generated within the broth. Thus, Pasteur dealt the death blow to the theory of spontaneous generation and supported Germ theory of disease.
In 1876,
Robert Koch established that microbes can cause disease. He did this by finding that the blood of cattle who were infected with
anthrax always had large numbers of
Bacillus anthracis. Koch also found that he could transmit anthrax from one animal to another by taking a small sample of blood from the infected animal and injecting it into a healthy one, causing the healthy animal to become sick. He also found that he could grow the bacteria in a nutrient broth, inject it into a healthy animal, and cause illness. Based upon these experiments, he devised criteria for establishing a causal link between a microbe and a disease in what are now known as Koch's postulates. The Nobel Prize in Physiology or Medicine 1905 Nobelprize.org Accessed November 22, 2006. Though these postulates cannot be applied in all cases, they do retain historical importance in the development of scientific thought and can still be used today.
Classification
showing the common ancestry of all three Domain (biology) of life.
Bacteria are colored blue,
eukaryotes red, and
archaea green. Relative positions of some
phylum are shown around the tree.Microorganisms can be found almost anywhere in the taxonomy organization of life on the planet. Bacteria and
archaea are almost always microscopic, while a number of
eukaryotes are also microscopic, including most
Protista and a number of
fungus.
Viruses are generally regarded as not living and therefore are not microbes, although the field of
microbiology also encompasses the study of viruses.
Prokaryotes
Prokaryotes are organisms that lack a
cell nucleus and the other
organelles found in
eukaryotes. Prokaryotes are almost always unicellular, although some such as
myxobacteria can aggregate into complex structures as part of their life cycle. These organisms are divided into two groups, the archaea and the bacteria.
Bacteria
bacteria magnified about 10,000x
Bacteria are the most diverse and abundant group of
organisms on
Earth. Bacteria inhabit practically all environments where some liquid water is available and the temperature is below +140 °C. They are found in sea water,
soil, animals' gastrointestinal tracts,
hot springs and even deep beneath the Earth's crust in Rock (geology)s. Practically all surfaces which have not been specially sterilized are covered in bacteria. The number of bacteria in the world is estimated to be around five million trillion trillion, or 5 × 1030.
Bacteria are practically all invisible to the naked eye, with few extremely rare exceptions, such as
Thiomargarita namibiensis. They are unicellular organisms and lack organelles. Their genome is usually a single loop of
DNA, although they can also harbor small pieces of DNA called plasmids. Bacteria are surrounded by a
cell wall, which provides strength and rigidity to their cells. They reproduce by
binary fission or sometimes by
budding. Some species form extremely resilient endospore, but for
bacteria this is a mechanism for survival, not reproduction. Under optimal conditions bacteria can grow extremely rapidly and can double as quickly as every 10 minutes.
Archaea
Archaea are also single-celled organisms that lack nuclei. In the past, the differences between bacteria and archaea were not recognised and archaea were classified with bacteria as part of the kingdom
Monera. Archaea differ from bacteria in their genetics and biochemistry. For example, while bacterial cell membranes are made from phospholipid with ester bonds, archaean membranes are made of ether lipids.
Archaea were originally described in extreme environments, such as
hot springs, but have since been found in all types of habitats. Only now are scientists beginning to appreciate how common archaea are in the environment, with crenarchaeota being the most common form of life in the ocean, dominating ecosystems below 150 m in depth. These organisms are also common in soil and play a vital role in ammonia oxidation.
Eukaryotes
, a typical
Eukaryote microorganismAll living things which are
individually visible to the naked eye are eukaryotes (with few exceptions, such as
Thiomargarita namibiensis), including humans. However, a large number of eukaryotes are also microorganisms. Unlike bacteria and
archaea, eukaryotes contain organelles such as the
cell nucleus, the Golgi apparatus and mitochondrion in their
cell (biology). The nucleus is an organelle which houses the
DNA that makes up a cell's genome. DNA itself is arranged in complex
chromosomes."Eukaryota: More on Morphology." (Accessed 10 October 2006)Mitochondria are organelles vital in metabolism as they are the site of the
citric acid cycle and
oxidative phosphorylation. They evolved from
symbiotic bacteria and retain a remnant genome. Like bacteria, plant cells have
cell walls, and contain organelles such as
chloroplasts in addition to the organelles in other eukaryotes. Chloroplasts produce energy from
light by photosynthesis, and were also originally symbiotic bacteria.
Unicellular eukaryotes are those eukaryotic organisms that consist of a single Cell (biology) throughout their life cycle. This qualification is significant since most multicellular organism eukaryotes consist of a single cell called a
zygote at the beginning of their life cycles. Microbial eukaryotes can be either
haploid or diploid, and some organisms have multiple
cell nucleus (see
coenocyte). However, not all microorganisms are unicellular as some microscopic eukaryotes are made from multiple cells.
Protists
Of
Eukaryote groups, the protists are most commonly unicellular and microscopic. This is a diverse group of organisms which are not easy to classify. Several
algae species are
multicellular protists, and
slime molds have unique life cycles with unicellular, colonial, and multicellular stages.
.
Animals
All animals are multicellular, but some are too small to be seen by the naked eye. Microscopic
arthropods include dust mites and spider mites. Microscopic crustaceans include
copepods and the
cladocera. Another common group of microscopic animals are the rotifers, which are filter feeders that are usually found in fresh water.
Fungi
The fungi have several unicellular species, such as baker's yeast (
Saccharomyces cerevisiae).
Plants
The green algae are a large group of photosynthetic eukaryotes that include many microscopic organisms. Although some green algae are classified as
protists, others such as
charophyta are classified with
embryophyte plants, which are the most familiar group of land plants.
Habitats and ecology
Microorganisms are found in almost every Habitat (ecology) present in nature. Even in hostile environments such as the geographical pole, deserts,
geysers,
Rock (geology)s, and the
deep sea, some types of microorganisms have adapted to the extreme conditions and sustained colonies; these organisms are known as
extremophiles. Extremophiles have been isolated from rocks as much as 7 kilometres below the earth's surface, and it has been suggested that the amount of living organisms below the earth's surface may be comparable with the amount of life on or above the surface. Extremophiles have been known to survive for a prolonged time in a vacuum, and can be highly resistant to ultraviolet radiation, which may even allow them to survive in space. Many types of microorganisms have intimate
symbiosis relationships with other larger organisms; some of which are mutually beneficial (mutualism), while others can be damaging to the host (biology) organism (
parasitism). If microorganisms can cause
disease in a host they are known as pathogens.
Extremophiles
Certain microbes have adapted so that they can survive and even thrive in conditions that are normally fatal to most lifeforms. Microorganisms have been found around underwater black smokers and in geothermal
hot springs, as well as in extremely salty bodies of water.
Soil microbes
The nitrogen cycle in soils depends on the fixation of atmospheric nitrogen. One way this can occur is in the nodules in the roots of legumes that contain symbiotic bacteria of the genera
Rhizobium,
Mesorhizobium,
Sinorhizobium,
Bradyrhizobium, and
Azorhizobium.
Symbiotic microbes
Symbiotic microbes
Importance
Microorganisms are vital to humans and the environment, as they participate in the Earth's element cycles such as the carbon cycle and nitrogen cycle, as well as fulfilling other vital roles in virtually all
ecosystems, such as recycling other organisms' dead remains and waste products through
decomposition. Microbes also have an important place in most higher-order multicellular organisms as
symbionts. Many blame the failure of Biosphere 2 on an improper balance of microbes.
Use in food
Microorganisms are used in
brewing, baking and other food-making processes.
The lactobacillus / lactobacilli and yeasts in sourdough bread are especially useful. To make bread, one uses a small amount (20-25%) of "
starter (fermentation)" dough which has the yeast
Microbiological culture, and mixes it with flour and water. Some of this resulting dough is then saved to be used as the starter for subsequent batches. The culture can be kept at room temperature and continue yielding bread for years as long as it remains supplied with new flour and water. This technique was often used when "on the trail" in the
American Old West.
Microorganisms are also used to control the Fermentation (food) process in the production of cultured dairy products such as yogurt and
cheese. The cultures also provide flavour and aroma, and to inhibit undesirable organisms.
Use in water treatment
Microbes are used in the biological treatment of sewage and industrial waste effluents.
Use in energy
Microbes are used in fermentation to produce ethanol.
Use in science
Microbes are also essential tools in biotechnology,
biochemistry, genetics, and
molecular biology.
Microbes can be harnessed for uses such as creating steroids and treating skin diseases. Scientists are also considering using microbes for living fuel cells, and as a solution for pollution.
Use in warfare
In the Middle Ages, dead corpses were thrown over walls during sieges, this meant that any bacteria carrying the disease that killed the person/creature would multiply in the vicinity of the opposing side.
Importance in human health
Human digestion
Microorganisms can form an
Endosymbiont relationship with other, larger, organisms. For example, the bacteria that live within the human digestive system contribute to gut immunity, synthesise
vitamins such as
folic acid and biotin, and ferment complex undigestible carbohydrates.
Diseases and immunology
Microorganisms are the cause of many infectious diseases. The organisms involved include bacteria, causing diseases such as bubonic plague, tuberculosis and
anthrax; protozoa, causing diseases such as malaria, sleeping sickness and toxoplasmosis; and also fungi causing diseases such as ringworm, candidiasis or histoplasmosis. However, other diseases such as influenza, yellow fever or AIDS are caused by
viruses, which are not living organisms and are not therefore microorganisms. As of 2007, no clear examples of archaean pathogens are known, although a relationship has been proposed between the presence of some methanogens and human
periodontal disease.
Hygiene
Hygiene is the avoidance of infection or
food spoiling by eliminating microorganisms from the surroundings. As microorganisms, particularly bacteria, are found practically everywhere, this means in most cases the reduction of harmful microorganisms to acceptable levels. However, in some cases it is required that an object or substance is completely sterile, i.e. devoid of all living entities and viruses. A good example of this is a hypodermic needle.
In food preparation microorganisms are reduced by preservation methods (such as the addition of vinegar), clean utensils used in preparation, short storage periods or by cool temperatures. If complete sterility is needed, the two most common methods are
irradiation and the use of an
autoclave, which resembles a
pressure cooker.
There are several methods for investigating the level of hygiene in a sample of food, drinking water, equipment etc. Water samples can be filtrated through an extremely fine filter. This filter is then placed in a
nutrient medium. Microorganisms on the filter then grow to form a visible colony. Harmful microorganisms can be detected in food by placing a sample in a nutrient broth designed to enrich the organisms in question. Various methods, such as
Selective medium or
PCR, can then be used for detection. The hygiene of hard surfaces, such as cooking pots, can be tested by touching them with a solid piece of nutrient medium and then allowing the microorganisms to grow on it.
There are no conditions where all microorganisms would grow, and therefore often several different methods are needed. For example, a food sample might be analyzed on three different nutrient mediums designed to indicate the presence of "total"
bacteria (conditions where many, but not all, bacteria grow), molds (conditions where the growth of bacteria is prevented by e.g.
antibiotics) and
Coliform Index bacteria (these indicate a sewage contamination).
In fiction
Microorganisms have frequently played an important part in
science fiction, both as agents of disease, and as entities in their own right.
Some notable uses of microorganisms in fiction include:
- The War of the Worlds, where microorganisms play important thematic and plot-related roles.
- Fantastic Voyage, in which some scientists are miniaturised to microscopic size and observe micro-organisms from a new perspective
- Blood Music, in which a colony of microorganisms is given intelligence
- The Andromeda Strain, in which extraterrestrial microorganisms kill several people
Twelve Monkeys, James Cole (Bruce Willis) searches for a pure germ in the past, which creates a deadly plague in the future. Also, Brad Pitt (as Jeffery Goines) discusses his germaphobia.
See also
References
External links
- Alliance for Consumer Education
- Understanding Our Microbial Planet: The New Science of Metagenomics A 20-page educational booklet providing a basic overview of metagenomics and our microbial planet.
- Microbe News from Genome News Network
- BBC News, 28 September, 2001: The microbes that 'rule the world' Citat: "... The Earth's climate may be dependent upon microbes that eat rock beneath the sea floor, according to new research....The number of the worm-like tracks in the rocks diminishes with depth; at 300 metres (985 feet) below the sea floor, they become much rarer..."
- BBCNews: 16 January, 2002, Tough bugs point to life on Mars Citat: "...This research demonstrates that certain microbes can thrive in the absence of sunlight by using hydrogen gas..."
- Microbes Patent List Microbes Related Patents
- BBCNews: 17 January, 2002, Alien life could be like Antarctic bugs
- Microbiology
- BURDEN of Resistance and Disease in European Nations - An EU-Project to estimate the financial burden of antibiotic resistance in European Hospitals
- Bioleaching microbes, BioMineWiki
Bacterium magnified 10,000 times.A
microorganism (also spelled as
microrganism) or
microbe is an
organism that is microscopic (too small to be seen by the human eye). The study of microorganisms is called
microbiology. Microorganisms include bacteria,
fungi,
archaea or protists, but not
viruses and
prions, which are generally classified as non-living. Most microorganisms are single-
cell (biology)ed, or
unicellular, but some are microscopic, and some unicellular protists are visible to the average human.
Microorganisms live almost everywhere on Earth where there is liquid
water, including
hot springs, on the
ocean floor, and deep inside rocks within Earth's
crust. Microorganisms are critical to nutrient recycling in
ecosystems as they act as
decomposers. As some microorganisms can also nitrogen fixation, they are an important part of the
nitrogen cycle. However, pathogenic microbes can invade other organisms and cause diseases that kill millions of people every year. 2002 WHO mortality data Accessed 20 January 2007
History
Evolution
Single-celled microorganisms were the Origin of life to develop on earth, approximately
1 E17 s. Further evolution was slow, and for about 3 billion years in the
Precambrian Eon (geology), all organisms were microscopic. So, for most of the history of life on Earth the only form of life were microorganisms. Bacteria, algae and fungi have been identified in
amber that is 220 million years old, which shows that the morphology of microorganisms have changed little since the triassic period.
Most microorganisms can reproduce rapidly and microbes such as bacteria can also freely exchange genes by Bacterial conjugation,
Transformation (genetics) and
Transduction (genetics) between widely-divergent species. This
horizontal gene transfer, coupled with a high
mutation rate and many other means of Bacteria#Genetic variation, allows microorganisms to swiftly biological evolution (via natural selection) to survive in new environments and respond to environmental stresses. This rapid evolution has led to the recent development of 'antibiotic resistance' — pathogenic
bacteria that are resistant to modern antibiotics.
Discovery
, the first person to observe microorganisms using a microscope
The existence of microorganisms was hypothesized during the late
Middle Ages but they were not observed or proven until the invention of the
microscope in the 17th century. In
The Canon of Medicine (1020),
Abū Alī ibn Sīnā (Avicenna) stated that bodily
secretion is contaminated by foul foreign earthly bodies before being infected, but he did not view them as primary causes of
disease. When the
Black Death bubonic plague reached
al-Andalus in the 14th century, Ibn Khatima and Ibn al-Khatib hypothesized that
infectious diseases are caused by microorganisms which enter the human body.Ibrahim B. Syed, Ph.D. (2002). "Islamic Medicine: 1000 years ahead of its times",
The Islamic Medical Association of North America 2, p. 2-9. Such ideas became more popular in Europe during the
Renaissance, particularly through the writing of the Italian monk
Girolamo Fracastoro.
Prior to Anton van Leeuwenhoek's discovery of microorganisms in 1675, it had been a mystery as to why
grapes could be turned into wine,
milk into cheese, or why food would spoil. Leeuwenhoek did not make the connection between these processes and microorganisms, but using the microscope, he did establish that there were forms of life that were not visible to the naked eye. Accessed 30 November 2006 Accessed 30 November 2006 Leeuwenhoek's discovery, along with subsequent observations by Lazzaro Spallanzani and
Louis Pasteur, ended the long-held belief that life
Abiogenesised from non-living substances during the process of spoilage.
Lazzarro Spallanzani found that microorganisms could only settle in a broth if the broth was exposed to the air. He also found that boiling the broth would Sterilization (microbiology) it and kill the microorganisms. Louis Pasteur expanded upon Spallanzani's findings by exposing boiled broths to the air, in vessels that contained a filter to prevent all particles from passing through to the growth medium, and also in vessels with no filter at all, with air being admitted via a curved tube that would not allow dust particles to come in contact with the broth. By boiling the broth beforehand, Pasteur ensured that no microorganisms survived within the broths at the beginning of his experiment. Nothing grew in the broths in the course of Pasteur's experiment. This meant that the living organisms that grew in such broths came from outside, as spores on dust, rather than spontaneously generated within the broth. Thus, Pasteur dealt the death blow to the theory of spontaneous generation and supported Germ theory of disease.
In 1876,
Robert Koch established that microbes can cause disease. He did this by finding that the blood of cattle who were infected with anthrax always had large numbers of
Bacillus anthracis. Koch also found that he could transmit anthrax from one animal to another by taking a small sample of blood from the infected animal and injecting it into a healthy one, causing the healthy animal to become sick. He also found that he could grow the bacteria in a nutrient broth, inject it into a healthy animal, and cause illness. Based upon these experiments, he devised criteria for establishing a causal link between a microbe and a disease in what are now known as
Koch's postulates. The Nobel Prize in Physiology or Medicine 1905 Nobelprize.org Accessed November 22, 2006. Though these postulates cannot be applied in all cases, they do retain historical importance in the development of scientific thought and can still be used today.
Classification
showing the common ancestry of all three Domain (biology) of life.
Bacteria are colored blue,
eukaryotes red, and archaea green. Relative positions of some
phylum are shown around the tree.Microorganisms can be found almost anywhere in the taxonomy organization of life on the planet. Bacteria and archaea are almost always microscopic, while a number of eukaryotes are also microscopic, including most Protista and a number of fungus. Viruses are generally regarded as not living and therefore are not microbes, although the field of
microbiology also encompasses the study of viruses.
Prokaryotes
Prokaryotes are organisms that lack a cell nucleus and the other
organelles found in
eukaryotes. Prokaryotes are almost always unicellular, although some such as
myxobacteria can aggregate into complex structures as part of their life cycle. These organisms are divided into two groups, the archaea and the bacteria.
Bacteria
bacteria magnified about 10,000x
Bacteria are the most diverse and abundant group of
organisms on Earth. Bacteria inhabit practically all environments where some liquid water is available and the temperature is below +140 °C. They are found in sea water,
soil, animals' gastrointestinal tracts, hot springs and even deep beneath the Earth's crust in
Rock (geology)s. Practically all surfaces which have not been specially sterilized are covered in bacteria. The number of bacteria in the world is estimated to be around five million trillion trillion, or 5 × 1030.
Bacteria are practically all invisible to the naked eye, with few extremely rare exceptions, such as
Thiomargarita namibiensis. They are
unicellular organisms and lack organelles. Their genome is usually a single loop of DNA, although they can also harbor small pieces of DNA called
plasmids. Bacteria are surrounded by a cell wall, which provides strength and rigidity to their cells. They reproduce by binary fission or sometimes by
budding. Some species form extremely resilient
endospore, but for
bacteria this is a mechanism for survival, not reproduction. Under optimal conditions bacteria can grow extremely rapidly and can double as quickly as every 10 minutes.
Archaea
Archaea are also single-celled organisms that lack nuclei. In the past, the differences between bacteria and archaea were not recognised and archaea were classified with bacteria as part of the kingdom Monera. Archaea differ from bacteria in their genetics and biochemistry. For example, while bacterial cell membranes are made from
phospholipid with
ester bonds, archaean membranes are made of
ether lipids.
Archaea were originally described in extreme environments, such as
hot springs, but have since been found in all types of habitats. Only now are scientists beginning to appreciate how common archaea are in the environment, with
crenarchaeota being the most common form of life in the ocean, dominating ecosystems below 150 m in depth. These organisms are also common in soil and play a vital role in
ammonia oxidation.
Eukaryotes
, a typical Eukaryote microorganismAll living things which are
individually visible to the naked eye are
eukaryotes (with few exceptions, such as
Thiomargarita namibiensis), including
humans. However, a large number of eukaryotes are also microorganisms. Unlike
bacteria and archaea, eukaryotes contain organelles such as the
cell nucleus, the
Golgi apparatus and mitochondrion in their
cell (biology). The nucleus is an organelle which houses the
DNA that makes up a cell's
genome. DNA itself is arranged in complex chromosomes."Eukaryota: More on Morphology." (Accessed 10 October 2006)Mitochondria are organelles vital in metabolism as they are the site of the
citric acid cycle and oxidative phosphorylation. They evolved from
symbiotic bacteria and retain a remnant genome. Like bacteria, plant cells have
cell walls, and contain organelles such as
chloroplasts in addition to the organelles in other eukaryotes. Chloroplasts produce energy from light by photosynthesis, and were also originally symbiotic bacteria.
Unicellular eukaryotes are those eukaryotic organisms that consist of a single
Cell (biology) throughout their life cycle. This qualification is significant since most multicellular organism eukaryotes consist of a single cell called a zygote at the beginning of their life cycles. Microbial eukaryotes can be either haploid or
diploid, and some organisms have multiple cell nucleus (see
coenocyte). However, not all microorganisms are unicellular as some microscopic eukaryotes are made from multiple cells.
Protists
Of Eukaryote groups, the protists are most commonly unicellular and microscopic. This is a diverse group of organisms which are not easy to classify. Several
algae species are multicellular protists, and slime molds have unique life cycles with unicellular, colonial, and multicellular stages.
.
Animals
All animals are multicellular, but some are too small to be seen by the naked eye. Microscopic
arthropods include dust mites and
spider mites. Microscopic crustaceans include
copepods and the
cladocera. Another common group of microscopic animals are the
rotifers, which are filter feeders that are usually found in fresh water.
Fungi
The fungi have several unicellular species, such as baker's yeast (
Saccharomyces cerevisiae).
Plants
The green algae are a large group of photosynthetic eukaryotes that include many microscopic organisms. Although some green algae are classified as
protists, others such as
charophyta are classified with embryophyte plants, which are the most familiar group of land plants.
Habitats and ecology
Microorganisms are found in almost every
Habitat (ecology) present in nature. Even in hostile environments such as the geographical pole,
deserts,
geysers,
Rock (geology)s, and the deep sea, some types of microorganisms have adapted to the extreme conditions and sustained colonies; these organisms are known as
extremophiles. Extremophiles have been isolated from rocks as much as 7 kilometres below the earth's surface, and it has been suggested that the amount of living organisms below the earth's surface may be comparable with the amount of life on or above the surface. Extremophiles have been known to survive for a prolonged time in a
vacuum, and can be highly resistant to ultraviolet radiation, which may even allow them to survive in space. Many types of microorganisms have intimate
symbiosis relationships with other larger organisms; some of which are mutually beneficial (
mutualism), while others can be damaging to the host (biology) organism (
parasitism). If microorganisms can cause disease in a host they are known as pathogens.
Extremophiles
Certain microbes have adapted so that they can survive and even thrive in conditions that are normally fatal to most lifeforms. Microorganisms have been found around underwater
black smokers and in geothermal
hot springs, as well as in extremely salty bodies of water.
Soil microbes
The
nitrogen cycle in soils depends on the fixation of atmospheric nitrogen. One way this can occur is in the nodules in the roots of
legumes that contain symbiotic bacteria of the genera
Rhizobium,
Mesorhizobium,
Sinorhizobium,
Bradyrhizobium, and
Azorhizobium.
Symbiotic microbes
Symbiotic microbes
Importance
Microorganisms are vital to humans and the environment, as they participate in the Earth's element cycles such as the
carbon cycle and
nitrogen cycle, as well as fulfilling other vital roles in virtually all
ecosystems, such as recycling other organisms' dead remains and waste products through
decomposition. Microbes also have an important place in most higher-order multicellular organisms as symbionts. Many blame the failure of Biosphere 2 on an improper balance of microbes.
Use in food
Microorganisms are used in brewing, baking and other food-making processes.
The lactobacillus / lactobacilli and yeasts in sourdough bread are especially useful. To make bread, one uses a small amount (20-25%) of "starter (fermentation)" dough which has the yeast
Microbiological culture, and mixes it with flour and water. Some of this resulting dough is then saved to be used as the starter for subsequent batches. The culture can be kept at room temperature and continue yielding bread for years as long as it remains supplied with new flour and water. This technique was often used when "on the trail" in the
American Old West.
Microorganisms are also used to control the
Fermentation (food) process in the production of cultured dairy products such as
yogurt and
cheese. The cultures also provide flavour and aroma, and to inhibit undesirable organisms.
Use in water treatment
Microbes are used in the biological treatment of sewage and industrial waste effluents.
Use in energy
Microbes are used in fermentation to produce ethanol.
Use in science
Microbes are also essential tools in
biotechnology,
biochemistry,
genetics, and
molecular biology. Microbes can be harnessed for uses such as creating steroids and treating skin diseases. Scientists are also considering using microbes for living fuel cells, and as a solution for pollution.
Use in warfare
In the Middle Ages, dead corpses were thrown over walls during sieges, this meant that any bacteria carrying the disease that killed the person/creature would multiply in the vicinity of the opposing side.
Importance in human health
Human digestion
Microorganisms can form an
Endosymbiont relationship with other, larger, organisms. For example, the bacteria that live within the human digestive system contribute to gut immunity, synthesise vitamins such as folic acid and
biotin, and ferment complex undigestible carbohydrates.
Diseases and immunology
Microorganisms are the cause of many infectious diseases. The organisms involved include
bacteria, causing diseases such as
bubonic plague,
tuberculosis and
anthrax; protozoa, causing diseases such as malaria, sleeping sickness and toxoplasmosis; and also fungi causing diseases such as ringworm,
candidiasis or
histoplasmosis. However, other diseases such as
influenza,
yellow fever or AIDS are caused by
viruses, which are not living organisms and are not therefore microorganisms. As of 2007, no clear examples of archaean pathogens are known, although a relationship has been proposed between the presence of some methanogens and human
periodontal disease.
Hygiene
Hygiene is the avoidance of infection or
food spoiling by eliminating microorganisms from the surroundings. As microorganisms, particularly
bacteria, are found practically everywhere, this means in most cases the reduction of harmful microorganisms to acceptable levels. However, in some cases it is required that an object or substance is completely sterile, i.e. devoid of all living entities and
viruses. A good example of this is a hypodermic needle.
In food preparation microorganisms are reduced by preservation methods (such as the addition of
vinegar), clean utensils used in preparation, short storage periods or by cool temperatures. If complete sterility is needed, the two most common methods are irradiation and the use of an
autoclave, which resembles a
pressure cooker.
There are several methods for investigating the level of hygiene in a sample of food, drinking water, equipment etc. Water samples can be filtrated through an extremely fine filter. This filter is then placed in a
nutrient medium. Microorganisms on the filter then grow to form a visible colony. Harmful microorganisms can be detected in food by placing a sample in a nutrient broth designed to enrich the organisms in question. Various methods, such as Selective medium or
PCR, can then be used for detection. The hygiene of hard surfaces, such as cooking pots, can be tested by touching them with a solid piece of nutrient medium and then allowing the microorganisms to grow on it.
There are no conditions where all microorganisms would grow, and therefore often several different methods are needed. For example, a food sample might be analyzed on three different
nutrient mediums designed to indicate the presence of "total" bacteria (conditions where many, but not all, bacteria grow), molds (conditions where the growth of
bacteria is prevented by e.g. antibiotics) and Coliform Index
bacteria (these indicate a sewage contamination).
In fiction
Microorganisms have frequently played an important part in science fiction, both as agents of disease, and as entities in their own right.
Some notable uses of microorganisms in fiction include:
- The War of the Worlds, where microorganisms play important thematic and plot-related roles.
- Fantastic Voyage, in which some scientists are miniaturised to microscopic size and observe micro-organisms from a new perspective
- Blood Music, in which a colony of microorganisms is given intelligence
- The Andromeda Strain, in which extraterrestrial microorganisms kill several people
Twelve Monkeys, James Cole (Bruce Willis) searches for a pure germ in the past, which creates a deadly plague in the future. Also, Brad Pitt (as Jeffery Goines) discusses his germaphobia.
See also
References
External links
- Alliance for Consumer Education
- Understanding Our Microbial Planet: The New Science of Metagenomics A 20-page educational booklet providing a basic overview of metagenomics and our microbial planet.
- Microbe News from Genome News Network
- BBC News, 28 September, 2001: The microbes that 'rule the world' Citat: "... The Earth's climate may be dependent upon microbes that eat rock beneath the sea floor, according to new research....The number of the worm-like tracks in the rocks diminishes with depth; at 300 metres (985 feet) below the sea floor, they become much rarer..."
- BBCNews: 16 January, 2002, Tough bugs point to life on Mars Citat: "...This research demonstrates that certain microbes can thrive in the absence of sunlight by using hydrogen gas..."
- Microbes Patent List Microbes Related Patents
- BBCNews: 17 January, 2002, Alien life could be like Antarctic bugs
- Microbiology
- BURDEN of Resistance and Disease in European Nations - An EU-Project to estimate the financial burden of antibiotic resistance in European Hospitals
- Bioleaching microbes, BioMineWiki
Definition: microorganism from Online Medical Dictionary
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Microorganism - Wikipedia, the free encyclopedia
A microorganism (also can be spelled as micro organism or micro-organism) or microbe is an organism that is microscopic (too small to be seen by the naked human eye).
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